I had intended to separate the two barriers people have, politics and science. Both need to be removed. Once a vaccine has bi-partisan support, the political barrier should evaporate.when people tell me they won’t take it, it’s not partisan. Some of the strongest Biden supporters I know are afraid to take it without at least a few years to see side effects. I think you’re overestimating People’s willingness to take an untested drug, as well as wrongfully connecting it to today’s politically charged atmosphere.
The safety concerns are a bit harder to overcome, but any vaccine released will likely have enough scientific evidence to prove that it's safe, or at least safer than risking getting the virus.