My guess is there will be more than the usual 1-2 differences this game. I think there will be some lineup changes due to rest and that these were not reflected in the release either because the decisions weren't made in time or the club is keeping that info under wraps (or combo of both).
Could definitely be the case, although my opinion is that we see more regular players than many here seem to assume. If there is any change from what we saw in the press release, I would guess Pirlo sits for Mix. Most of the younger guys can handle the extra games, although you could claim the Birthday Boy (Pirlo) could handle it too since he paces himself so well.